Impaired verbal memory is associated with impaired motor performance in schizophrenia: relationship to brain structure

Content Provider	Semantic Scholar
Author	Manschreck, Theo C. Maher, Brendan A. Candela, Steven F. Redmond, Deborah Tsuang, Ming T.
Copyright Year	2000
Abstract	Deficient ability to take advantage of predictable elements in the performance of cognitive tasks has been proposed as an underlying factor for a number of deviances in schizophrenia. In a schizophrenic sample (n=39), we propose and test the view that certain memory and motor anomalies arise because of a compromise in the capacity to take advantage of the redundant (predictable) features of cognitive tasks. Results demonstrate a relationship between reduced capacity to take advantage of predictable features of two different cognitive processing tasks, one verbal memory, and the other motor. Poorer verbal recall on high-redundancy word lists was associated with a reduced ability to produce synchronous finger tapping in response to a high redundancy auditory stimulus, and inversely correlated with formal thought disorder ratings. These relationships, we suggest, reflect a specific and common schizophrenic deficit in the use of redundancies, not attributable to a generalized deficiency in performance. Structural imaging evidence from a subsample of these subjects (n=16) implicates frontal areas as the locus of this cognitive impairment.
Starting Page	21
Ending Page	32
Page Count	12
File Format	PDF HTM / HTML
DOI	10.1016/S0920-9964(99)00179-6
PubMed reference number	10828412
Journal	Medline
Volume Number	43
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/S0920996499001796
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/S0920996499001796?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/S0920-9964%2899%2900179-6
Journal	Schizophrenia Research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article