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The Effect of 17 Β-estradiol on Ca 1 Hyppocampal Neurogenesis during the Aging Process
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yadegari, Zahra Ghorbanian, Mohammad Taghi Vaezi, Gholamhassan Hojati, Vida |
| Copyright Year | 2014 |
| Abstract | The aging process affects all body tissues including the brain and different hormones reduced with age in mammals. This research was performed to study the effects of hormonal changes during the aging process on neurogenesis in the hippocampus. The female Wistar rats were divided into five groups including prepubertal, pubertal in metestrus phase, pubertal treated with 17β-estradiol, post-pubertal in metestrus phase and post-pubertal treated with 17β-estradiol. The groups received 50 μg/kg 17β-estradiol subcutaneously daily injections for 7 days. Groups in metestrus phase were detected in based on the observed cells in the vaginal smear. The results revealed that cell proliferation along with 17beta-estradiol injection in the CA1 region of hippocampus was increased and cell proliferation in the adult group was significantly higher than the after puberty group. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.cibtech.org/J-LIFE-SCIENCES/PUBLICATIONS/2014/Vol-4-No-2/JLS-048-061-HOJATI-THE-PROCESS.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
