Hydrophobic forces and hydrogen bonds in the adhesion between retinoid-coated surfaces.

Content Provider	Semantic Scholar
Author	Tareste, David Pincet, Frederic Lebeau, Luc Pérez, Eric
Copyright Year	2007
Abstract	Interactions between hydrophobic chains of lipid monolayers and interactions between hydrophilic headgroups of lipid bilayers (with or without a molecular recognition step) are now well documented, especially for commonly used lipids. Here, we report force measurements between a new class of fluorinated lipid layers whose headgroups (synthetic ligands of retinoid receptors) display a very unusual polar/apolar character and can interact via a combination of hydrophobic forces and hydrogen bonds. Although these two interactions produce adhesion and are therefore not easily distinguishable, we show that it is possible to extract both contributions unambiguously. Experiments are performed both in pure water, where the adhesion is a combination of hydrophobic forces and hydrogen bonds, and in Tris buffer, where the hydrophobic effect is the dominant short-range attractive force. The contribution of hydrophobic forces scaled down to molecular interactions is deduced from force versus distance profiles, and the same value is found independently in pure water and Tris buffer, about 1 kBT. We also show that retinoid lipid layers attract each other through a very long-range (100 nm) exponential force, which is insensitive to the pH and the salinity. The origin of this long-range attraction is discussed on the basis of previously proposed mechanisms.
Starting Page	89
Ending Page	98
Page Count	10
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.lps.ens.fr/IMG/pdf/retinoide_langmuir_07.pdf
PubMed reference number	17266339v1
Volume Number	23
Issue Number	6
Journal	Langmuir : the ACS journal of surfaces and colloids
Language	English
Access Restriction	Open
Subject Keyword	Buffers Document completion status - Documented Ligands Lipid Metabolism Disorders Retinoids Tris(2,3-dibromopropyl) Phosphate Tromethamine anatomical layer exponential
Content Type	Text
Resource Type	Article