Loading...
Please wait, while we are loading the content...
Similar Documents
Clinical inquiries. Are topical nitrates safe and effective for upper extremity tendinopathies?
| Content Provider | Semantic Scholar |
|---|---|
| Author | Nguyen, Long H. Kelsberg, Gary Beecher, Debbie Safranek, Sarah |
| Copyright Year | 2014 |
| Abstract | Topical nitrates provide shortterm relief with some side effects, especially headache. Topical nitroglycerin (NTG) patches improve subjective pain scores by about 30% and range of motion over 3 days in patients with acute shoulder tendinopathy (strength of recommendation [SOR]: C, small randomized controlled trial [RCT] with no methodologic flaws). NTG patches, when combined with tendon rehabilitation, improve subjective pain ratings by about 30% and shoulder strength by about 10% in patients with chronic shoulder tendinopathy over 3 to 6 months, but not in the long term (SOR: C, RCTs with methodologic flaws). They improve pain and strength 15% to 50% for chronic extensor tendinosis of the elbow over a 6-month period (SOR: C, small RCT with methodologic flaws). NTG patches used without tendon rehabilitation don’t improve pain or strength in chronic lateral epicondylitis over 8 weeks (SOR: C, RCT). Topical NTG patches commonly produce headaches and rashes (SOR: B, multiple RCTs). |
| File Format | PDF HTM / HTML |
| PubMed reference number | 25350256 |
| Journal | Medline |
| Volume Number | 63 |
| Issue Number | 8 |
| Alternate Webpage(s) | https://www.mdedge.com/sites/default/files/Document/September-2017/JFP_06308_ClinInquiry1.pdf |
| Journal | The Journal of family practice |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
