NDLI: Synthesis and evaluation of novel 17-indazole androstene derivatives designed as CYP17 inhibitors

Content Provider	Semantic Scholar
Author	Moreira, Vania M. Vasaitis, Tadas Sean Njar, Vincent C. O. Salvador, Jorge A. R.
Copyright Year	2007
Abstract	A series of novel 1H- and 2H-indazole derivatives of the commercially available dehydroepiandrosterone acetate have been synthesized and tested for inhibition of human cytochrome 17alpha-hydroxylase-C(17,20)-lyase (CYP17), androgen receptor (AR) binding affinity, and cytotoxic potential against three prostate cancer (PC) cell lines.
Starting Page	939
Ending Page	948
Page Count	10
File Format	PDF HTM / HTML
DOI	10.1016/j.steroids.2007.08.004
Alternate Webpage(s)	https://www.ibbr.umd.edu/printpdf/20219
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/S0039128X07001390
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/S0039128X07001390?dgcid=api_sd_search-api-endpoint
PubMed reference number	17884122
Alternate Webpage(s)	https://doi.org/10.1016/j.steroids.2007.08.004
Journal	Medline
Volume Number	72
Journal	Steroids
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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