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Lack of prognostic value of type D personality for mortality in a large sample of heart failure patients.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Coyne, James Charles Jaarsma, Tiny Luttik, M. L. A. Sonderen, Eric Van Veldhuisen, Dirk Jan Van Sanderman, Robbert |
| Copyright Year | 2011 |
| Abstract | BACKGROUND Type D personality has been proposed as a prognostic indicator for mortality in cardiovascular disease. Most research examining this construct originates from one research group, and it is critical that the predictive value of Type D personality for adverse outcomes is independently cross-validated. This study examined its prognostic value in heart failure, relative to B-type natriuretic peptide (BNP) and depressive symptoms. METHODS We studied 706 patients with complete BNP, depressive symptom, and Type D personality and mortality data from 958 patients with heart failure enrolled after hospitalization for a multisite study of a disease management program. Multivariable models were adjusted for BNP and depression. RESULTS At 18 months, there were 192 deaths (27.2%). No evidence was found for a prognostic value of Type D personality in the unadjusted model (hazard ratio [HR] = 0.893, 95% confidence interval [CI] = 0.582-1.370). In contrast, BNP was significantly predictive of mortality (HR = 1.588, 95% CI = 1.391-1.812), whereas depression was not (HR = 1.011, 95% CI = 0.998-1.024). Type D was also not predictive in covariate-adjusted models (HR = 0.779, 95% CI = 0.489-1.242). Similar results were obtained when analyzing Type D as the interaction between continuous z scores of its two components, negative affectivity and social inhibition (p = .144). CONCLUSIONS In the largest study to date, Type D does not predict mortality. Future research should construe Type D as the interaction of continuous negative affectivity and social inhibition z scores, rather than as a typology, and consider analyses replacing negative affectivity with depression. |
| Starting Page | 301 |
| Ending Page | 311 |
| Page Count | 11 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://liu.diva-portal.org/smash/get/diva2:446347/FULLTEXT01.pdf |
| PubMed reference number | 21862826v1 |
| Alternate Webpage(s) | https://doi.org/10.1097/PSY.0b013e318227ac75 |
| DOI | 10.1097/psy.0b013e318227ac75 |
| Journal | Psychosomatic medicine |
| Volume Number | 73 |
| Issue Number | 7 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Cardiovascular Diseases Cessation of life Confidence Intervals Depressive Symptoms Depressive disorder Disease Management Heart failure Hospitalization Nesiritide Patients negative regulation of type IV pilus biogenesis |
| Content Type | Text |
| Resource Type | Article |
