NDLI: Patients With Neurogenic Lower Urinary Tract Dysfunction Following Spinal Cord Injury Are at Increased Risk of Developing Type 2 Diabetes Mellitus

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Patients With Neurogenic Lower Urinary Tract Dysfunction Following Spinal Cord Injury Are at Increased Risk of Developing Type 2 Diabetes Mellitus

Content Provider	Semantic Scholar
Author	Lien, Wei-Chih Kuan, T. S. Lin, Yu-Ching Liang, Fu-Wen Hsieh, Pei-Chun Li, Chung-yi Wall, Patrick
Copyright Year	2016
Abstract	To investigate whether patients with neurogenic lower urinary tract dysfunction (NLUTD) following spinal cord injury (SCI) are at increased risk of developing type 2 diabetes mellitus (T2DM).The retrospective cohort study used a subset of the Taiwan National Health Insurance Research Database (NHIRD) comprising information on 2 million beneficiaries randomly sampled from the general population. A total of 3515 patients with newly diagnosed SCI were identified during the period of 2001 to 2008. Among them, 170 developed NLUTD following SCI. The control group was consisted of 656 patients without NLUTD over the study period randomly selected by matching NLUTD cases on the date of NLUTD incidence, age, sex, and duration since diagnosis of SCI. The study groups were then followed to the end of 2009. T2DM was the end-point.The incidence rate ratios of T2DM were higher in the NLUTD group than in the control group (4.94 vs. 2.61 per 10,000 person-years), representing an adjusted hazard ratio (AHR) of 1.70 (95% confidence interval [CI] 1.11-2.61). Age-specific AHR was significantly elevated only in patients aged > = 60 years (AHR = 2.52 (95% CI 1.35-4.70)).This study showed that the NLUTD following SCI may significantly increase the risk of developing T2DM.
Starting Page	1864
Ending Page	1868
Page Count	5
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://ftp.ncbi.nlm.nih.gov/pub/pmc/23/83/medi-95-e2518.PMC4718302.pdf
PubMed reference number	26765476v1
Alternate Webpage(s)	https://doi.org/10.1097/MD.0000000000002518
DOI	10.1097/md.0000000000002518
Journal	Medicine
Volume Number	95
Language	English
Access Restriction	Open
Subject Keyword	Confidence Intervals Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus, Non-Insulin-Dependent Hazard Ratio Patients Sampling - Surgical action Spinal Cord Injuries Spinal Cord Neoplasms Subgroup Urinary tract Vocal Cord Paralysis
Content Type	Text
Resource Type	Article

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