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The wavelengths in sunlight effective in producing skin cancer: a theoretical analysis.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Setlow, Richard B. |
| Copyright Year | 1974 |
| Abstract | DNA is taken as the target for skin cancer induced by ultraviolet light, and the known data on the sensitivity of DNA as a function of wavelength are summarized. The sun's spectrum at the surface of the earth and the DNA action spectrum are used to calculate the carcinogenic effectiveness as a function of wavelength. The most effective wavelengths at 30 degrees N latitude are <305 nm, and a 1% change in atmospheric ozone results in a 2% change in the effective dose of ultraviolet light. Since both the basic biological and physical data are reasonably precise, the major requirement for a quantitative evaluation of the dose response relation for ultraviolet-induced skin cancer in man is better epidemiological data to compare with data from animal models. |
| Starting Page | 97 |
| Ending Page | 111 |
| Page Count | 15 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.pnas.org/content/71/9/3363.full.pdf |
| PubMed reference number | 4530308v1 |
| Volume Number | 71 |
| Issue Number | 9 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Animal Model Dermatologic disorders Epidemiology Latitude:Angle:Point in time:Cancer.To be specified in another part of the message:Quantitative Malignant neoplasm of skin Ozone Ultraviolet Rays wavelength |
| Content Type | Text |
| Resource Type | Article |