NDLI: Antagonis Soluble Fms-Like Tyrosine Kinase 1 (sFlt-1) dan Soluble Endoglin (sEng) pada Preeklamsia

Content Provider	Semantic Scholar
Author	Andalas, Mohd Harahap, Harahap
Copyright Year	2017
Abstract	Proangiogenic factor signal transduction like vascular endothelial growth factor (VEGF), placental growth factor (PlGF) and tissue growth factor â-1 (TGFâ-1) are important to angiogenesis and vascular health in pregnancy. In preeclampsia (PE) concentration of fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin (sEng) are increase significantly. Base on analysis from resent research shown that sFlt-1 and sEng inhibit angiogenic factor signal transduction by competition in result angiogenic factor can‘t bind to their receptor. sFlt-1 and sEng are potential used as preeclampsia therapy because sFlt-1 and sEng have main role in PE pathogenesis. We suggest that the research to find out effective sFlt-1 and sEng antagonist have to conduct in the next time.
Starting Page	1
Ending Page	1
Page Count	1
File Format	PDF HTM / HTML
DOI	10.26891/jik.v4i1.2010.1-9
Volume Number	4
Alternate Webpage(s)	http://jik.fk.unri.ac.id/index.php/jik/article/viewFile/5/2
Alternate Webpage(s)	https://doi.org/10.26891/jik.v4i1.2010.1-9
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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