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Synthesis and optical characterization of Er 3 + : Y 2 O 3 nanocrystals show their potential
| Content Provider | Semantic Scholar |
|---|---|
| Author | Nash, Kelly L. |
| Copyright Year | 2007 |
| Abstract | There has been a great deal of interest in the fabrication and characterization of highly luminescent nanoparticles because of their potential applications as nanosensors and as biosensors for applications such as molecular diagnostics. The organic dyes currently used in biomedical applications of imaging and immunoassays have advantages such as commercial availability and high quantum yield, but they also have disadvantages such as broad spectral band, short fluorescence lifetime and photobleaching. In contrast, rare-earth (RE) nanoparticles exhibit sharp line emission bands, reasonably large Stokes shifts and long fluorescence lifetimes, and they can be encapsulated in neutral environments to avoid toxic reactions. In addition, rareearth nanoparticles have a high quantum yield and excellent photostability. These nanoparticles can enable time-resolved fluorescence imaging for quantitative detection of antigens as well as tissue-specific transcripts and genes. They have the potential to be used for noninvasive, nondestructive and real-time in vivo diagnosis of various diseases, including atherosclerotic plaques, which can lead to stroke and heart disease.1 Optimized rare earth-based nanoparticles could be useful for nanosensors, bioprobes, drug discovery, medical diagSynthesis and optical characterization of Er:Y2O3 nanocrystals show their potential. by Dhiraj K. Sardar, Kelly L. Nash and John B. Gruber, University of Texas at San Antonio, and Anthony Sayka, Maxim Integrated Products Rare Earth-Doped Nanocrystals for Biosensing and Imaging |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://physics.utsa.edu/laserlab/publications/papers/2008/B%20I%20_RE%20Nanoparticles%20.pdf |
| Alternate Webpage(s) | https://www.utsa.edu/physics/faculty/SardarLab/pubs/2008-bi15.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |