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Correlation between Fibrinogen Levels and Glycated Hemoglobin in Patients with Diabetes Mellitus Type 2
| Content Provider | Semantic Scholar |
|---|---|
| Author | Pedro-González, Ez Alejandra Huerta-Ramírez, Saúl Cerda-Téllez, Ez Fidel Geuguer-Chávez, Ez Lizbeth López-Véjar, Ar César Emmanuel |
| Copyright Year | 2014 |
| Abstract | Background: It has been reported a pathophysiological relationship between fibrinogen and atherosclerosis, thrombosis, inflammation, and coronary events, as well as between better glycemic control and fewer complications. objective: To determine whether there is a correlation between the concentrations of fibrinogen and glycosylated hemoglobin in diabetic patients. Material and method: A transversal analytical study was done with data from 29 patients. Pearson correlation was performed for glycosylated hemoglobin (HbA1c) and fibrinogen, for qualitative variables U Mann-Whitney and Fisher's exact tests were used. STATA version 11 was used. results: Of the 29 patients analyzed, we found a mean glucose of 186.9 ± 62.7 mg/dL, mean HbA1c of 9.69 ± 2.8%, and mean fibrinogen of 445.6 ± 106 mg/dL. A correlation between HbA1c and fibrinogen was found (r = 0.24, p = 0.19). Patients with diabetic retinopathy had a mean fibrinogen of 521 ± 78 mg/dL and patients without retinopathy had a mean fibrinogen of 425 ± 104 mg/dL (p = .03). Conclusion: No significant correlation was found between fibrinogen and HbA1c. High fibrinogen levels are significantly associated with diabetic retinopathy. |
| Starting Page | 24 |
| Ending Page | 31 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| Volume Number | 30 |
| Alternate Webpage(s) | https://www.cmim.org/boletin/pdf2014/MedIntContenido01_04.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
