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Differences among dystrophic, dwarf, and their crossbred mice in the time course of changes in extracellular muscle action potentials induced by 5-Hz stimulation
| Content Provider | Semantic Scholar |
|---|---|
| Author | Totsuka, Tsuyoshi Watanabe, Kimi Uramoto |
| Copyright Year | 1984 |
| Abstract | With urethane anesthesia, extracellular action potentials were recorded in medial gastrocnemius muscles of dystrophic, dwarf, and their crossbred mice. When repetitive stimulation was delivered at 5 Hz for a relatively long period, characteristic features were revealed. (i) Dystrophic mice showed a slight decrease or even an increase in action potentials whereas in littermate normal mice the amplitudes were rapidly and notably reduced. (ii) In both dwarf and their littermate normal mice, a considerable reduction in amplitude was observed. Slightly more depression was produced than in nondystrophic mice of a comparable age. (iii) Crossbred mice were in two classes. A rapid and notable reduction in the amplitude of muscle action potentials was observed in one class, and slight changes in the potentials were produced in another class showing dystrophy-specific symptoms. |
| Starting Page | 616 |
| Ending Page | 626 |
| Page Count | 11 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0014-4886(84)90209-7 |
| PubMed reference number | 6723883 |
| Journal | Medline |
| Volume Number | 84 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/0014488684902097 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/0014488684902097?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0014-4886%2884%2990209-7 |
| Journal | Experimental Neurology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
