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The association between occupational factors and adverse health outcomes in chronic obstructive pulmonary disease.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Blanc, Paul David Eisner, Mark David Trupin, Laura Yelin, Edward H. Katz, Patricia P. Balmes, John R. |
| Copyright Year | 2004 |
| Abstract | BACKGROUND AND AIMS Despite recognition that occupational exposures may make a substantive contribution to the aetiology of COPD, little is known about the potential role of work related factors in COPD related health outcomes. METHODS Prospective cohort study using structured telephone interviews among a random sample of adults aged 55-75 reporting a COPD condition (emphysema, chronic bronchitis, or COPD). Using multivariate models adjusting for smoking and demographic factors, the separate and combined associations were estimated between occupational exposure to vapours, gas, dust, or fumes (VGDF) and leaving work due to lung disease (respiratory related work disability) with health outcomes and utilisation ascertained at one year follow up. RESULTS Of 234 subjects, 128 (55%) reported exposure to VGDF on their longest held jobs, 58 (25%) reported respiratory related work disability, and 38 (16%) subjects reported both. Combined exposure to VGDF and respiratory related work disability (rather than either factor alone) was associated with the greatest risk at follow up of frequent (everyday) restricted activity days attributed to a breathing or lung condition (OR 3.8; 95% CI 1.4 to 10.1), emergency department (ED) visit (OR 3.9; 95% CI 1.4 to 10.5), and hospitalisation (OR 7.6; 95% CI 1.8 to 32). CONCLUSIONS Among persons with COPD, past occupational exposures and work disability attributed to lung disease, particularly in combination, appear to be risk factors for adverse health related outcomes. |
| Starting Page | 182 |
| Ending Page | 185 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://oem.bmj.com/content/oemed/61/8/661.full.pdf |
| PubMed reference number | 15258271v1 |
| Volume Number | 61 |
| Issue Number | 8 |
| Journal | Occupational and environmental medicine |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Accident and Emergency department Bronchitis Bronchitis, Chronic Chronic Obstructive Airway Disease Departure - action Health Outcomes Hospitalization Lung Diseases, Obstructive Lung diseases Mental association Occupational Diseases Occupations Pulmonary Emphysema Random Sampling Respiratory Insufficiency Smoke fume |
| Content Type | Text |
| Resource Type | Article |
