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Five-year follow-up of the Argentine randomized trial of coronary angioplasty with stenting versus coronary bypass surgery in patients with multiple vessel disease (ERACI II).
| Content Provider | Semantic Scholar |
|---|---|
| Author | Rodríguez, Alfredo E. Baldi, Julio Pereira, Carlos Fernández Navia, José Alemparte, Máximo Rodríguez Delacasa, Alejandro Vigo, Federico Vogel, Daniel M. O'neill, William Palacios, Igor F. |
| Copyright Year | 2005 |
| Abstract | OBJECTIVES The purpose of the present study is to report the five-year follow-up results of the ERACI II trial. BACKGROUND Immediate and one-year follow-up results of the ERACI II study showed a prognosis advantage of percutaneous coronary intervention (PCI) with stents over coronary artery bypass grafting (CABG). METHODS A total of 450 patients were randomly assigned to undergo either PCI (n = 225); or CABG (n = 225). Only patients with multi-vessel disease were enrolled. Clinical follow-up during five years was obtained in 92% of the total population after hospital discharge. The primary end point of the study was to compare freedom from major adverse cardiovascular events (MACE) at 30 days, 1 year, 3 years, and 5 years of follow-up. RESULTS At five years of follow-up, patients initially treated with PCI had similar survival and freedom from non-fatal acute myocardial infarction than those initially treated with CABG (92.8% vs. 88.4% and 97.3% vs. 94% respectively, p = 0.16). Freedom from repeat revascularization procedures (PCI/CABG) was significantly lower with PCI compared with CABG (71.5% vs. 92.4%, p = 0.0002). Freedom from MACE was also significantly lower with PCI compared with CABG (65.3% vs. 76.4%; p = 0.013). At five years similar numbers of patients randomized to each revascularization procedure were asymptomatic or with class I angina. CONCLUSIONS At five years of follow-up, in the ERACI II study, there were no survival benefits from any revascularization procedure; however patients initially treated with CABG had better freedom from repeat revascularization procedures and from MACE. |
| Starting Page | 195 |
| Ending Page | 198 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.onlinejacc.org/content/accj/46/4/582.full.pdf?download=true |
| PubMed reference number | 16098419v1 |
| Volume Number | 46 |
| Issue Number | 4 |
| Journal | Journal of the American College of Cardiology |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Angina Pectoris Cardiovascular Diseases Coronary Artery Bypass Surgery Coronary Artery Disease Follow-Up Report Forecast of outcome Myocardial Infarction Numerous Paget's Disease, Mammary Patients Percutaneous Coronary Intervention PersonNameUse - assigned Stent, device benefit revascularization |
| Content Type | Text |
| Resource Type | Article |
