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Rôle des progéniteurs dans l'hypertension artérielle pulmonaire humaine et expérimentale
| Content Provider | Semantic Scholar |
|---|---|
| Author | Gambaryan, Natalia |
| Copyright Year | 2011 |
| Abstract | Pulmonary arterial hypertension (PAH) is a group of diseases characterized by avascular obstruction leading to a progressive increase of the resistances in the pulmonary blood flow. The recent progress in the understanding of mechanisms at the origin of this disease underlines the role of extrapulmonary cells, such as circulating stem cells and bone marrow-derived progenitor cells in vascular remodeling and in PAH development. In this thesis we have shown implication of the progenitor cells and chemotactic axis in the vascular remodeling in human and experimental PAH. This work could help to develop new therapies allowing more specific and more effective treatments leading to improved survival of PAH patients. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://tel.archives-ouvertes.fr/tel-00639980/document |
| Alternate Webpage(s) | https://tel.archives-ouvertes.fr/file/index/docid/639980/filename/VA1_GAMBARYAN_NATALIA_04072011.pdf |
| Alternate Webpage(s) | http://hal.inria.fr/docs/00/63/99/80/PDF/VA1_GAMBARYAN_NATALIA_04072011.pdf |
| Alternate Webpage(s) | http://www.theses.fr/2011PA11T036.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |