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Cardiac myxomas: 24 years of experience in 49 patients.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Keeling, Ingeborg Marianne Oberwalder, Peter J. Anelli-Monti, Michael Schuchlenz, Herwig Walter Demel, Ulrike Tilz, Gernot P. Rehak, Peter Rigler, Bruno |
| Copyright Year | 2002 |
| Abstract | OBJECTIVES In this single-center study we reviewed our experience with a significant number of cardiac myxoma cases occurring over the past two decades. PATIENTS AND METHODS Cardiac myxomas represented 86% of all surgically treated cardiac tumors at our center. Specifically, there were 49 consecutive patients, each with at least one myxoma. A detailed clinical, immunological, and echocardiographic long-term examination of 37 patients revealed one recurrent myxoma. RESULTS Most myxomas originated from the left atrium (87.7%), but also much less frequently from the mitral valve (6.1%), from the right atrium (4.1%), and from the left and right atria (2.0%). The myxomas produced a prolapse into the left ventricle in 40.8% of the patients, mitral stenosis in 10.2%, and threatened left ventricular outflow tract obstruction in 2.0%. Multiple myxomas were found in 20.4% of the patients. Cardiac signs appeared in 93.9% of the patients. Preoperative embolic events had occurred in 26.5%. Immunologic alterations were present in 87.5%. For resection, a bilateral atriotomy was used. An additional aortotomy was needed to expose one mitral valve myxoma. Postoperatively, 81.1% of the patients remained without cardiac symptoms. The early mortality rate was 2.0% and the late mortality rate was 6.1%. Long-term prognosis was excellent with an actuarial survival rate of 0.74. Specific immunologic alterations were found in 71.4% of the patients. The actuarial freedom from reoperation of the myxoma was 0.96. The rate of reoperations was low with 2.0% after 24 years. CONCLUSIONS Myxomas were usually detected and operated on in symptomatic patients. A high index of suspicion seems important for early diagnosis. Immunologic findings may play an additional role in confirming the diagnosis and the recurrence of a myxoma. Immediate surgical treatment was indicated because of the high risk of embolization or of sudden cardiac death. Also, a familial genesis must be excluded in myxoma patients. |
| Starting Page | 69 |
| Ending Page | 74 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://watermark.silverchair.com/22-6-971.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAawwggGoBgkqhkiG9w0BBwagggGZMIIBlQIBADCCAY4GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM3Zz1xXhtfIbmUTKVAgEQgIIBXzqRHA5ZAtWGnNbkjUbF0PT1-V2sE9e6mnMoXVHZQZsQ4JlThfUA6ZDT0QIJJJbdqA4zZTYN7uvR9tIYwvfYkXMHe2BtySpr4V6NRBw7fIHmFnbp2oYAIbEyzkJPj7ea33w-AUtuc7xfHEVqY8YsxIr6eCnGIqElsHUbHJ6IioWKsVwul38ry3uQY_yjg3ZXt2uDzY3pg_uijMOeZOAIK3vwWukVYBupUB5CO0DeXFI2CqxKFuQjOdkslr4VisPVwEg-1Xt3bML_abzONBj6gf-ty2OYbmjop1tJJDq2FSwTK4MBTm-movNr0yzZuZW7y1nZ6DINiVB0TcNEg8lSnJYTkFqUGyP5f2uruGpofpyzxgeQZEKi-_OA2p4I4j3aKRTXCz812sKYxG3x4N5KcpfTedxSt50lIGB6QLtpvESQy4Xg9m3XwfRkc1ACXAn8JxPr3UrXsCsSJfnmHsfhdA |
| PubMed reference number | 12467822v1 |
| Volume Number | 22 |
| Issue Number | 6 |
| Journal | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Artificial cardiac pacemaker Early Diagnosis Embolism Excision Exclusion Forecast of outcome Forty Nine Heart Atrium Heart Neoplasm Heart Ventricle Immune System Diseases Immunologic Techniques Left atrial structure Left ventricular outflow tract obstruction Left ventricular structure Mitral Valve Stenosis Myxoma of heart Myxoma of the Endocardium Neoplasms Operative Surgical Procedures Patients Premature ventricular contractions Ptosis Repeat Surgery Right atrial structure Sudden Cardiac Death cardiac symptom |
| Content Type | Text |
| Resource Type | Article |
