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Contribution of NeuroImaging for Prediction of Functional Recovery after Ischemic Stroke
| Content Provider | Semantic Scholar |
|---|---|
| Author | Heiss, Wolf-Dieter |
| Copyright Year | 2017 |
| Abstract | Prediction measures of recovery and outcome after stroke perform with only modest levels of accuracy if based only on clinical data. Prediction scores can be improved by including morphologic imaging data, where size, location, and development of the ischemic lesion is best documented by magnetic resonance imaging. In addition to the primary lesion, the involvement of fiber tracts contributes to prognosis, and consequently the use of diffusion tensor imaging (DTI) to assess primary and secondary pathways improves the prediction of outcome and of therapeutic effects. The recovery of ischemic tissue and the progression of damage are dependent on the quality of blood supply. Therefore, the status of the supplying arteries and of the collateral flow is not only crucial for determining eligibility for acute interventions, but also has an impact on the potential to integrate areas surrounding the lesion that are not typically part of a functional network into the recovery process. The changes in these functional networks after a localized lesion are assessed by functional imaging methods, which additionally show altered pathways and activated secondary centers related to Received: June 13, 2017 Accepted: July 18, 2017 Published online: September 5, 2017 Wolf-Dieter Heiss, MD Max Planck Institute for Metabolism Research Gleueler Str. 50 DE–50931 Cologne (Germany) E-Mail wdh @ sf.mpg.de © 2017 S. Karger AG, Basel |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.karger.com/Article/Pdf/479594 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Antigens Arteries Cerebral Infarction Cerebrovascular accident Cologne - Zebrafish Color gradient Conflict (Psychology) Data recovery Database Decision Making Diffusion Tensor Imaging Disclosure Document completion status - Documented Eligibility Determination Functional Imaging Rehabilitation therapy Resonance Scientific Publication Sheffer stroke Silver Tissue fiber Wolf-Hirschhorn Syndrome |
| Content Type | Text |
| Resource Type | Article |
