NDLI: Specific amino acids of Olive mild mosaic virus coat protein are involved in transmission by Olpidium brassicae.

Please wait, while we are loading the content...

Specific amino acids of Olive mild mosaic virus coat protein are involved in transmission by Olpidium brassicae.

Content Provider	Semantic Scholar
Author	Varanda, Carla M. R. Félix, Maria Do Rosário Soares, Cláudio M. Oliveira, Solange Clara, Maria Ivone Esteves
Copyright Year	2011
Abstract	Transmission of Olive mild mosaic virus (OMMV) is facilitated by Olpidium brassicae (Wor.) Dang. An OMMV mutant (OMMVL11) containing two changes in the coat protein (CP), asparagine to tyrosine at position 189 and alanine to threonine at position 216, has been shown not to be Olpidium brassicae-transmissible owing to inefficient attachment of virions to zoospores. In this study, these amino acid changes were separately introduced into the OMMV genome through site-directed mutagenesis, and the asparagine-to-tyrosine change was shown to be largely responsible for the loss of transmission. Analysis of the structure of OMMV CP by comparative modelling approaches showed that this change is located in the interior of the virus particle and the alanine-to-threonine change is exposed on the surface. The asparagine-to-tyrosine change may indirectly affect attachment via changes in the conformation of viral CP subunits, altering the receptor binding site and thus preventing binding to the fungal zoospore.
File Format	PDF HTM / HTML
DOI	10.1099/vir.0.032284-0
PubMed reference number	21593272
Journal	Medline
Volume Number	92
Part	9
Alternate Webpage(s)	http://www.microbiologyresearch.org/docserver/fulltext/jgv/92/9/2209_vir032284.pdf?accname=guest&checksum=2F21DD6DB7BB9FD81B2AB3FD6D93A9BE&expires=1544564435&id=id
Alternate Webpage(s)	http://www.microbiologyresearch.org/docserver/fulltext/jgv/92/9/2209_vir032284.pdf?accname=guest&checksum=66F4E45235AEAC23243060EA9B4A10FC&expires=1499396201&id=id
Alternate Webpage(s)	http://dspace.uevora.pt/rdpc/bitstream/10174/2816/3/Abstract.pdf
Alternate Webpage(s)	https://doi.org/10.1099/vir.0.032284-0
Journal	The Journal of general virology
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in