Role of bacterial effectors SopD and SopB in pathogenicity of Salmonella enterica serovar Typhimurium.

Content Provider	Semantic Scholar
Author	Bakowski, Malina A.
Copyright Year	2009
Abstract	ii Acknowledgements iv Table of contents v-vi List of Abbreviations viii-x List of Tables xi List of Figures xii-xiii List of Publications Used in Thesis xiv Chapter 1 – Introduction..................................................................... 1 Phagocytosis of Pathogens......................................................... 1 a) The Process of Phagocytosis 1 b) Phagocytic Receptors 1 c) Particle Engulfment: Lipids and GTPases 4 1. Lipids 7 2. GTPases 11 d) Phagosome Maturation 14 1. Early Endosomes and Phagosomes 14 2. Late Endosomes and Phagosomes 17 3. Lysosomes and Phagolysosomes 17 e) Additional Microbicidal Phagosome Factors 18 1. ROS and RNS 19 2. CAMPs 20 3. Antigen Presentation 20 f) Prevailing over Phagocytosis: Pathogen Strategies 21 1. Preventing Phagosome Maturation 21 Chlamydia spp. 23 Legionella pneumophila 24 Brucella spp. 24 Mycobacterium tuberculosis 25 2. Invading Non-Phagocytic Cells 26 Zipper Mechanism of Invasion 26 Trigger Mechanism of Invasion 27 Salmonella enterica.................................................................... 30 a) Salmonella enterica serovar Typhimurium Infection 30
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Resource Type	Article