Loading...
Please wait, while we are loading the content...
A Study of Adverse Drug Reactions in Cancer Patients Due to Chemotherapy in a Tertiary Care Hospital , Rims , Ranchi
| Content Provider | Semantic Scholar |
|---|---|
| Author | Keshri, Uma Shanker Prasad Kavitakumari Mahato, Sumitkumar Akhilesh Kumar Protim, Pholgu |
| Copyright Year | 2017 |
| Abstract | Adverse drug reactions (ADRs) are adverse or unintended effects associated with medications and these are also associated with the use of anticancer drugs which have become a worldwide problem and monitoring these reaction are essential for safety of patient and prompt management is necessary for adherence to chemotherapy. Material And Method:This is a retrospective study done in department of pharmacology in association with dept. of oncology Rims, Ranchi. Those patients who developed reaction during chemotherapy were included in this study taking either single or combination drug therapy. The causality assessment of the monitored ADRs were determined using WHO-UMC Causality Scale. Result And Discussion: A total of 104 patient were included this study, of which 62 were female and 42 were male. Total of 236 ADR were incurred during chemotherapy. 53% were gastrointestinal ADR followed by haematologicalADR 16%, C.N.S related ADR accounted for 12% followed by Skin 9%, Cardiovascular 3%, Renal 2% and others 5%. Causality assessment by WHO-UMC in our study was possible( 86%), probable( 13%), certain( 1%), unlikely(0%), unclassified(0%), unassessable( 0%). Conclusion:Monitoring and management of ADR is essential for success of chemotherapy. As these ADR may steer the patient to make a judgment for stopping the medications and finally the occurrence of drug resistance and an amplified healthcare cost. If a proper educational system is implemented, so that most of the patients may report their ADR which may help to improve the patients adherence and therapeutic outcome. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://iosrjournals.org/iosr-jdms/papers/Vol16-issue8/Version-5/U1608058993.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
