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Labour induction at term--a randomised trial comparing Foley catheter plus titrated oral misoprostol solution, titrated oral misoprostol solution alone, and dinoprostone.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Matonhodze, Baron B. Hofmeyr, G. Justus Levin, Jonathan C. |
| Copyright Year | 2003 |
| Abstract | OBJECTIVES To compare three methods of labour induction. DESIGN Randomised controlled trial. SETTING Academic hospitals in Johannesburg, South Africa. SUBJECTS Women with intact membranes due for induction of labour. METHOD Randomised, sealed opaque envelopes were used to allocate women to labour induction with extra-amniotic Foley catheter/titrated oral misoprostol solution (N = 174), titrated oral misoprostol solution alone (N = 176), or vaginal dinoprostone (N = 176). Misoprostol was dissolved in water and 20-40 g was given 2-hourly. OUTCOME MEASURES These were failure to deliver vaginally within 24 hours, additional measures for induction or augmentation of labour, analgesia, and maternal and fetal complications. RESULTS In the Foley catheter group, misoprostol was required in all but 1 case. Failure to deliver vaginally within 24 hours was similar for the three groups (79/174 v. 70/176 v. 70/176 respectively). Labour augmentation, caesarean section and instrumental delivery were used somewhat more frequently in the Foley/misoprostol group than in the misoprostol alone group, but these differences were not statistically significant. More analgesia was used in the Foley catheter/misoprostol group than in the misoprostol group (64/172 v. 46/175). Side-effects and neonatal complications were similar for the three groups. CONCLUSIONS Use of extra-amniotic Foley catheter placement showed no measurable benefits over the use of oral misoprostol alone, or vaginal dinoprostone. |
| File Format | PDF HTM / HTML |
| DOI | 10.7196/SAMJ.2166 |
| PubMed reference number | 12830603 |
| Journal | Medline |
| Volume Number | 93 |
| Issue Number | 5 |
| Alternate Webpage(s) | http://www.samj.org.za/index.php/samj/article/viewFile/2166/1444 |
| Alternate Webpage(s) | https://www.ajol.info/index.php/samj/article/download/132258/121854 |
| Alternate Webpage(s) | https://doi.org/10.7196/SAMJ.2166 |
| Journal | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
