Blessure et réparation épithéliale : une hypothèse physiopathologique de la polypose nasosinusienne

Content Provider	Semantic Scholar
Author	Lazard, Diane Prulière-Escabasse, Virginie Papon, Jean-François Escudier, Estelle Coste, André
Copyright Year	2007
Abstract	Key points Nasal polyposis (NP), asthma, and chronic bronchitis are chronic inflammatory diseases of the upper airways. They may be caused by injury to the respiratory epithelium in a chronic inflammatory environment. Several studies show that during NP nasal epithelial cells are involved in the overexpression of cytokines and growth factors. Among these, transforming growth factor β1 (TGF-β1) appears to play a major role in the genesis of NP. Differentiated respiratory epithelium, obtained from in vivo or in vitro models, is used to study wound healing in inflammatory environments, to elucidate the pathophysiology of NP, and to improve understanding and management of upper airway inflammatory diseases.
File Format	PDF HTM / HTML
DOI	10.1016/j.lpm.2007.01.021
Alternate Webpage(s)	https://www.em-consulte.com/showarticlefile/103360/main.pdf
Alternate Webpage(s)	https://doi.org/10.1016/j.lpm.2007.01.021
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article