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Synthesis And Antibacterial Activity Of 3-[ ( 3-Phenyl-5-Thioxo-1 , 5-Dihydro-4 h-1 , 2 , 4-Triazol-4-Yl ) Imino ]-1 , 3-Dihydro-2 h-Indole-2One
| Content Provider | Semantic Scholar |
|---|---|
| Author | Singh, Neelottma Chattree, Amit |
| Copyright Year | 2016 |
| Abstract | A series of 3-[(3-phenyl-5-thioxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)imino]-1,3-dihydro-2Hindole-2-one derivatives were synthesised through the nucleophilic substitution at carbonyl carbon of Isatin. Structure of synthesized compounds were elucidated by using IR, 1 H NMR & 13 C NMR spectrometry. Synthesised compounds showed significant antibacterial activity against E.coli (ATCC 35218), S.aureus (ATCC 25323), E.faecalis (Clinical isolate), K. Pneumonia, P. aeruginosa (ATCC 27893) using agar well diffusion method. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.ijpsi.org/Papers/Vol5(8)/A05080106.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |