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P078 Nutritional Status and Growth in Pediatric Crohn's Disease (cd): a Population Based Study
| Content Provider | Semantic Scholar |
|---|---|
| Author | Rzehak, Peter Lohr, Wolfgang Gębora-Kowalska, Beata Kudzin, Joanna Plocek, Anna Biernacka, Elżbieta Katarzyna Gower-Rousseau, C. Vernier-Massouille, Gwénola Dupas, Jean-Louis Merle, Véronique Merlin, Béatrice Lerebours, Eric Salomez, J. Uchida, Keiko Inoue, Mikihiro Ohtake, Kouhei Koike, Yuhki Matsushita, Kazuhiro Araki, Toshimitsu Yoshiyama, Shigeyuki Ohkita, Yoshiki Tanaka, Kouji Miki, Chikao Kusunoki, Masato Kutluk, Gunsel Ertem, Deniz Pehlivanoğlu, Ender Dolinšek, Jernej Mičetić-Turk, Dušanka |
| Copyright Year | 2009 |
| Abstract | Objective: To define the effect of age & sex on disease location in CD by two statistical approaches in patients aged 0 16 from the CEDATA registry. Age was examined as a continuous variable and grouped. Location was examined grouped (Montreal) and dichotomized (small bowel, large bowel, upper GI only). To examine differences in mean age ANOVA was used. To examine the strength of the association for dichotomized locations by age group logistic regression was applied. Analyses were based on 1064 cases. Mean age (yrs) was as follows: L1 Small bowel, 13.8 (+ upper GI (L4), 13.5); L2 large bowel, 12.2 (+ L4, 12.9); L3 small and large, 12.9 (+ L4 12.6); L 4 upper GI only, 12.3. Differences between L1 and L2 (p < 0.001) and L1 and L3 (p = 0.02) were statistically significant. There was no effect of sex, but centre size contributed significant interaction. The risk for small bowel involvement was very low in young children (age 0 5; OR 0.19, 95% CI 0.06 to 0.63) and increased with age (age 6 10 OR 0.48, 95% CI 0.30 to 0.77; age 11 13 OR 0.58, 95% CI 0.40 to 0.97; reference: age 14 16). In contrast, the OR for large bowel involvement in young children (0 5 yrs) was 1.96 (1.12 to 3.45) and decreased with age. Odds ratios for girls (vs. boys) were strongly decreased for isolated upper GI involvement (OR 0.13, 95% CI 0.03 to 0.54). Conclusion: Small vs. large bowel involvement is dependent on age but not sex, while upper GI location is determined by sex but not age. Future analyses will explore evolution over time. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://watermark.silverchair.com/3-1-18b.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAbUwggGxBgkqhkiG9w0BBwagggGiMIIBngIBADCCAZcGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMB8B1mHgwBxwCgXoGAgEQgIIBaA_OBjmRdYFVPOQFcaqOnW1tO5yakJfUoa5xf_WgsiBztgrZpveKbaygMcIsugbLaQxwrIF3AlWu2VCyVivwVwNKObnyou2D7RO6zbmzFrTfIkYNiR1UygVdNGUt2fxYr0oDb7YrTMupG1AlA-ufK6x8YFDW_Cwa1ojwn6S7EKXox1kAWV8wfNBf-Lo1Gq70QqUrcQKvyCDyDr9f72lFmEvDn7rOz4w3Ky-XIQTxSSNk-u-BfD1kf9X0K7A4sgZUkgpzVogNtaYXPQC5EX3UmZ7_807xy0FdhQWRJuh6JXusbb-QDRemETf1Anbfrx20F9D94VBogtQzcCvuY76dBUc3onTHNM1wojVAi6clX44jghoSQ5Vgd8kMcv20EFWvXcEhoILJRsWYUkw87L4yOcQ8_vZL4MOTKvArRsbHA-qdPS2PU0wMZEoqgccswWBGp9ZC6OJcFbNiGYTXLbx_gEuTzd79eZCjsA |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Crohn Disease Female child Intestines Intestines, Small Large Intestinal Wall Tissue Large Intestine Logistic regression Patients Registries Small Intestinal Wall Tissue Status Epilepticus Upper Gastrointestinal Tract |
| Content Type | Text |
| Resource Type | Article |
