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Characterization in Drosophila melanogaster of dPDZ-GEF, a Rap GTPase activator
| Content Provider | Semantic Scholar |
|---|---|
| Author | Antoine-Bertrand, Judith |
| Copyright Year | 2007 |
| Abstract | Proper regulation of celi adhesion, migration, proliferation and survival is essential for the maintenance of cellular equilibrium. Any upset of that balance, however small it is, can precipitate celis into a chain of events that can lead to numerous pathologies, including cancer. for instance, activating mutations in some members of the Ras-MAPK pathway are involved in the formation of tumours in 30% of all human cancers. Dr. Therrien’s laboratory studies the function of members of the Ras-MAPK pathway in Drosophila meÏanogaster, one of the most ftequently used model organisms in the study of signal |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://papyrus.bib.umontreal.ca/xmlui/bitstream/handle/1866/15605/Antoine-Bertrand_Judith_2006_memoire.pdf?isAllowed=y&sequence=1 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |