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Molecular characterization of infectious bursal disease virus (IBDV): Diversity of very virulent IBDV in Tanzania
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kasanga, Christopher Jacob Yamaguchi, Tomohiro Wambura, Philemon Nyangi Maeda-Machang'u, A. D. Ohya, Kenji Fukushi, Hideto |
| Copyright Year | 2006 |
| Abstract | SummaryNucleotide sequences of the VP2 hypervariable region (VP2-HVR) of 14 infectious bursal disease viruses (IBDVs) isolated in Tanzania from 2001 to 2004 were determined. Phylogenetic analysis showed that the isolates diverged into two genotypes and belonged to the very virulent (VV) type. In the phylogenetic tree, strains in one genotype clustered in a distinct group and were closely related to some strains isolated in western Africa, with nucleotide similarities of 96.1–96.8%, while strains in another genotype were clustered within the European/Asian VV type with nucleotide similarities ranging from 97.5 to 99.3%. Both genotypes were widely distributed throughout Tanzania, and had conserved putative virulence marker amino acids (aa) at positions 222(A), 242(I), 256(I), 294(I) and 299(S). Our findings demonstrate for the first time the existence of both African and European/Asian VV-IBDV variants in Tanzania. |
| Starting Page | 783 |
| Ending Page | 790 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| DOI | 10.1007/s00705-006-0898-5 |
| PubMed reference number | 17226068 |
| Journal | Medline |
| Volume Number | 152 |
| Alternate Webpage(s) | http://achengula.weebly.com/uploads/2/3/2/3/23230900/molecular_characterization_of_infectious_bursal_disease_virus_ibdv__diversity_of_very_virulent_ibdv_in_tanzania_-_springer.pdf |
| Alternate Webpage(s) | https://doi.org/10.1007/s00705-006-0898-5 |
| Journal | Archives of Virology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
