Loading...
Please wait, while we are loading the content...
Similar Documents
Does exercise reduce inflammation? Physical activity and C-reactive protein among U.S. adults.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ford, Earl S. |
| Copyright Year | 2002 |
| Abstract | BACKGROUND Physical activity may lower the risk for coronary heart disease by mitigating inflammation, which plays a key role in the pathophysiology of atherosclerosis. The purpose of this study was to examine the association between physical activity and C-reactive protein concentration in a national sample of the U.S. population. METHODS The analytic sample included 13,748 participants >or=20 years of age in the National Health and Nutrition Examination Survey III (1988-1994) with complete data for the main study variables. RESULTS After adjusting for age, sex, ethnicity, education, work status, smoking status, cotinine concentration, hypertension, body mass index, waist-to-hip ratio, high-density lipoprotein cholesterol concentration, and aspirin use, the odds ratios for elevated C-reactive protein concentration (dichotomized at the >or=85th percentile of the sex-specific distribution) were 0.98 (95% confidence interval = 0.78-1.23), 0.85 (0.70-1.02), and 0.53 (0.40-0.71) for participants who engaged in light, moderate, and vigorous physical activity, respectively, during the previous month compared with participants who did not engage in any leisure-time physical activity. In addition, leisure-time physical activity was positively associated with serum albumin concentration and inversely associated with both log-transformed plasma fibrinogen concentration and log-transformed white blood cell count. CONCLUSIONS These results add to mounting evidence that physical activity may reduce inflammation, which is a critical process in the pathogenesis of cardiovascular disease. |
| File Format | PDF HTM / HTML |
| DOI | 10.1097/01.EDE.0000023965.92535.C0 |
| PubMed reference number | 12192226 |
| Journal | Medline |
| Volume Number | 13 |
| Issue Number | 5 |
| Alternate Webpage(s) | https://www.drperlmutter.com/wp-content/uploads/2013/07/Preview-of-%E2%80%9CPrint%E2%80%9D3.pdf |
| Alternate Webpage(s) | https://doi.org/10.1097/01.EDE.0000023965.92535.C0 |
| Journal | Epidemiology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
