NDLI: Gonadotropin-controlled mammal oocyte meiotic resumption.

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Gonadotropin-controlled mammal oocyte meiotic resumption.

Content Provider	Semantic Scholar
Author	Zhang, Meijia Xia, G. P. Zhou, Bo Wang, Chao
Copyright Year	2007
Abstract	Fully grown mammalian oocytes resume meiosis as a consequence of rises in gonadotropin levels at the mid-cycle. The increase of cyclic adenosine 3',5'-monophosphate (cAMP) and the activation of protein kinase A (PKA), protein kinase C (PKC) and mitogen-activated protein kinase (MAPK) in cumulus cells are required for gonadotropins-induced meiotic resumption of oocytes. The various actions of cAMP activated by follicle-stimulating hormone (FSH) and luteinizing hormone (LH) also include meiosis activating sterol (MAS), gonadal steroid hormones and epidermal growth factor (EGF) network during meiotic resumption. Another second messenger guanosine 3',5'-cyclic monophosphate (cGMP) induced by nitric oxide (NO) or atrial natriuretic peptide (ANP) also mediates gonadotropins-controlled mammalian oocyte meiotic resumption. The different actions of FSH and LH on meiotic resumption are discussed. We hope to provide a framework to understand how the initial signals generated by gonadotropins-stimulation control the expression of genes required for meiotic resumption.
Starting Page	85
Ending Page	91
Page Count	7
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.bioscience.org/fbs/getfile.php?FileName=/2007/v12/af/2064/2064.pdf
PubMed reference number	17127299v1
Volume Number	12
Journal	Frontiers in bioscience : a journal and virtual library
Language	English
Access Restriction	Open
Subject Keyword	8-Bromo Cyclic Adenosine Monophosphate Atrial Natriuretic Factor Cyclic AMP Cyclic AMP-Dependent Protein Kinases Cyclic GMP Cyclic adenosine monophosphate measurement Follicle Stimulating Hormone Gonadal structure Gonadorelin Gonadotropins Guanosine Tetraphosphate Heart Atrium Mammals Meiosis Mitogen-Activated Protein Kinases Mitogens Nitric Oxide Oocytes Ovarian Follicle Protein Kinase C Steroid hormone Steroids Stimulation (motivation)
Content Type	Text
Resource Type	Article

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