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Design and synthesis of novel inhibitors of gelatinase B.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Wang, Xueqing Choe, Youngchool Craik, Charles S. Ellman, Jonathan A. |
| Copyright Year | 2002 |
| Abstract | A new method was developed to identify nonpeptidic metalloproteinase inhibitors with novel zinc binding groups. Application of this method to matrix metalloproteinase-9 resulted in the identification of aminomethyl benzimidazole analogue 7a with an IC(50)=13 microM. |
| Starting Page | 96 |
| Ending Page | 100 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.craiklab.ucsf.edu/docs/pub181.pdf |
| PubMed reference number | 12127537v1 |
| Volume Number | 12 |
| Issue Number | 16 |
| Journal | Bioorganic & medicinal chemistry letters |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Analog Benzimidazoles Gelatinases Matrix Metalloproteinase 9 Maxillary right lateral incisor abutment Metalloproteases zinc ion binding |
| Content Type | Text |
| Resource Type | Article |
