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Synthesis of 11α-hydroxyprogesterone hartens
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yoshida, Hirokazu Nakai, S. Nimbari, Fusako Yoshimoto, Kiyoko Nishimura, Tadashi |
| Copyright Year | 1989 |
| Abstract | Abstract C-4 and C-6 bridged haptens of 11α-hydroxyprogesterone, an anti-androgen, were respectively synthesized via 4,5 and 5α,6α epoxide ring openings using 3-mercaptopropanoic acid. Substitution of 6-bromo derivative of progesterone using the same reagent unexpectedly afforded a C-4 substituted product instead of the normal C-6 substituted product previously reported in the literature. |
| Starting Page | 727 |
| Ending Page | 738 |
| Page Count | 12 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0039-128X(89)90063-9 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/0039128X89900639 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/0039128X89900639?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0039-128X%2889%2990063-9 |
| Volume Number | 53 |
| Journal | Steroids |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |