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Modi fi cation and quanti fi cation of in vivo EROD live-imaging with zebra fi sh ( Danio rerio ) embryos to detect both induction and inhibition of CYP 1 A
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kais, Britta Ottermanns, Richard Scheller, Franziska Braunbeck, Thomas |
| Copyright Year | 2017 |
| Abstract | • Chlorpyrifos is a strong CYP1A inhibitor in zebrafish embryos. • Aroclor 1254 inhibits CYP1A catalytic activity in zebrafish embryos in a specific time-dependent manner. • CYP1A inhibition could also be detected after 3 h short-term exposure of zebrafish embryos to chlorpyrifos. • The lack of CYP1A inhibition after 3 h exposure of zebrafish embryos to Aroclor 1254 demonstrates toxicokinetic mecha- |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.bio5.rwth-aachen.de/ro/pubs/kais_modification_and_quantification_of_in_vivo_EROD_2017.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |