NDLI: Influenza virus proteins: identity, synthesis, and modification analyzed by two-dimensional gel electrophoresis.

Content Provider	Semantic Scholar
Author	Privalsky, Martin L. Penhoet, Edward E.
Copyright Year	1978
Abstract	A modification of the two-dimensional protein electrophoresis system of O'Farrell was used to resolve influenza A virus proteins from each other and from host proteins in infected cells. Viral protein spots corresponding to the hemagglutinin proteins, neuraminidase, nucleocapsid protein, and nonstructural protein, were identified on the two-dimensional electrophoretogram. Use of the two-dimensional separation has allowed us to identify glycoprotein heterogeneity, to demonstrate directly the synthesis of neuraminidase, to analyze some viral proteins early after infection, and to demonstrate that the influenza virus NP and NS proteins are phosphorylated in infected MDCK cells.
File Format	PDF HTM / HTML
DOI	10.1073/pnas.75.8.3625
Alternate Webpage(s)	http://www.pnas.org/content/75/8/3625.full.pdf
PubMed reference number	278978
Alternate Webpage(s)	https://doi.org/10.1073/pnas.75.8.3625
Journal	Medline
Volume Number	75
Issue Number	8
Journal	Proceedings of the National Academy of Sciences of the United States of America
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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