In vitro antioxidant activity of Vetiveria Zizanioides root extract.

Content Provider	Semantic Scholar
Author	Subhadradevi, Varadharajan Asokkumar, Kuppusamy Umamaheswari, Muthuswamy Sivashanmugam, Andichettiarthirumalasia Sankaranand, Rajakannu
Copyright Year	2010
Abstract	Free radicals induce numerous diseases by lipid peroxidation and DNA damage. It has been reported that some of the extracts from plants possess antioxidant properties capable of scavenging free radicals in vivo. Vetiveria zizanioides belonging to the family Gramineae, is a densely tufted grass which is widely used as a traditional plant for aromatherapy, to relieve stress, anxiety, nervous tension and insomnia. In this regard, the roots of V zizanioides was extracted with ethanol and used for the evaluation of various in vitro antioxidant activities such as reducing power ability, superoxide anion radical scavenging activity, deoxyribose degradation assay, total antioxidant capacity, total phenolics and total flavonoid composition. The various antioxidant activities were compared with suitable antioxidants such as butyl hydroxy toluene, ascorbic acid, quercetin, alpha tocopherol, pyrocatechol and curcumin respectively. The generation of free radicals O2, H2O2 OH and N O were effectively scavenged by the ethanolic extract of V zizanioides. In all these methods, the extract showed strong antioxidant activity in a dose dependent manner. The results obtained in the present study clearly indicates that V zizanioides scavenges free radicals, ameliorating damage imposed by oxidative stress in different disease conditions and serve as a potential source of natural antioxidant. The study provides a proof for the ethnomedical claims and reported biological activities. The plant has, therefore, very good therapeutic and antioxidant potential.
Starting Page	1
Ending Page	4
Page Count	4
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.ajol.info/index.php/thrb/article/download/56401/44836
Alternate Webpage(s)	https://tspace.library.utoronto.ca/bitstream/1807/63384/1/th10037.pdf
PubMed reference number	24409635v1
Volume Number	12
Issue Number	4
Journal	Tanzania journal of health research
Language	English
Access Restriction	Open
Subject Keyword	Anions Antioxidants Anxiety Disorders Aromatherapy and Essential Oils Ascorbic Acid Curcumin Deoxyribose Ethanol Extraction Flavonoids Free Radicals Hydrogen Peroxide Hydroxyl Radical In Vitro [Publication Type] Lipid Peroxidation Nervousness Oxidative Stress Plant Roots Poaceae Quercetin Sleeplessness Superoxides Toluene Vetiveria alpha Tocopherol antioxidant activity catechol hydroxyl group tert-Butyl Alcohol
Content Type	Text
Resource Type	Article