Loading...
Please wait, while we are loading the content...
Similar Documents
Dental pain induced by an ambient thermal differential: pathophysiological hypothesis
| Content Provider | Semantic Scholar |
|---|---|
| Author | Fur-Bonnabesse, Anaïs Le Bodéré, Céline Hélou, Cyrielle Chevalier, Valérie Goulet, Jean-Paul |
| Copyright Year | 2017 |
| Abstract | Dental pain triggered by temperature differential is a misrecognized condition and a form of dental allodynia. Dental allodynia is characterized by recurrent episodes of diffuse, dull and throbbing tooth pain that develops when returning to an indoor room temperature after being exposed for a long period to cold weather. The pain episode may last up to few hours before subsiding. Effective treatment is to properly shield the pulpal tissue of the offending tooth by increasing the protective layer of the dentin/enamel complex. This review underscores the difference in dentin hypersensitivity and offers a mechanistic hypothesis based on the following processes. Repeated exposure to significant positive temperature gradients (from cold to warm) generates phenotypic changes of dental primary afferents on selected teeth with subsequent development of a "low-grade" neurogenic inflammation. As a result, nociceptive C-fibers become sensitized and responsive to innocuous temperature gradients because the activation threshold of specific TRP ion channels is lowered and central sensitization takes place. Comprehensive overviews that cover dental innervation and sensory modalities, thermodynamics of tooth structure, mechanisms of dental nociception and the thermal pain are also provided. |
| Starting Page | 2845 |
| Ending Page | 2851 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.dovepress.com/getfile.php?fileID=39744 |
| PubMed reference number | 5736355 |
| Alternate Webpage(s) | https://doi.org/10.2147/JPR.S142539 |
| DOI | 10.2147/jpr.s142539 |
| Journal | Journal of pain research |
| Volume Number | 10 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | CNS disorder Conflict (Psychology) Dentin Sensitivity Drug Allergy Ion Channel Iontophoresis Neurogenic Inflammation Nociception Odontogenic Tissue Pain Patients Sensitization (observable entity) Singular Sodium Fluoride 0.0024 MG/MG Toothpaste Sodium monofluorophosphate 0.0076 MG/MG Toothpaste Thermodynamics Tissue fiber Tooth structure Toothache Tryptophan nerve supply |
| Content Type | Text |
| Resource Type | Article |
