NDLI: RNA editing in Newcastle disease virus.

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RNA editing in Newcastle disease virus.

Content Provider	Semantic Scholar
Author	Steward, Michael G. Vipond, I. Barry Millar, Neil S.
Copyright Year	1993
Abstract	The co-transcriptional editing of the Newcastle disease virus (NDV) P gene has been studied by sequence analysis of cloned viral genomic RNA and mRNA. Evidence has been obtained for the specific insertion of non-templated G nucleotides, the consequence of which is the generation of three populations of P gene-derived mRNAs. The three populations encode proteins (P, V and W) which have a common N-terminal region, but which utilize three different reading frames at their C termini. Paradoxically, NDV edits its P gene mRNA by the insertion of non-templated G residues in a manner similar to Sendai and measles viruses (P-->V editing) despite its apparent closer evolutionary relationship to the simian virus type 5, mumps and related group of viruses which edit a V genomic sequence to generate an mRNA to encode a functional P protein (V-->P editing).
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://vir.sgmjournals.org/content/74/12/2539.full.pdf
Alternate Webpage(s)	http://www.microbiologyresearch.org/docserver/fulltext/jgv/74/12/JV0740122539.pdf?accname=guest&checksum=528ECC21F81C66A6123529349A7B0D6E&expires=1540962488&id=id
Alternate Webpage(s)	http://www.microbiologyresearch.org/docserver/fulltext/jgv/74/12/JV0740122539.pdf?accname=guest&checksum=4968C4F6742668C191895FADB05B301B&expires=1543901289&id=id
PubMed reference number	8277263v1
Volume Number	74
Part	12
Journal	The Journal of general virology
Language	English
Access Restriction	Open
Subject Keyword	Clinical act of insertion Clone Cells Encode (action) Frame (physical object) Insertion Mutation Moloney murine sarcoma virus Murine sarcoma viruses Newcastle disease virus Nucleotides RNA Editing Reading Frames (Nucleotide Sequence) Sequence Analysis Transcription, Genetic
Content Type	Text
Resource Type	Article

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