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Cutaneous adverse drug reactions profile in a tertiary care hospital in North India
| Content Provider | Semantic Scholar |
|---|---|
| Author | Brar, Balvinder Kaur Kaur, Jashandeep Kumar, Sumir Sethi, Naveen Kumar, Raj |
| Copyright Year | 2018 |
| Abstract | Objective To document drugs causing the cutaneous adverse effects and the morphology of these reactions. Methods This observational study was carried out at Department of Dermatology in a tertiary care hospital for two years to study the cutaneous adverse drug reactions (cADRs) and identify the culprit drug or drugs. A total of 188 patients reporting to dermatology department with cutaneous adverse drug reactions were evaluated. Detailed history, as well as, clinical examination findings were recorded along with investigations wherever required and feasible. Results The commonest drug reaction was found to be fixed drug eruptions (29.2%) followed by urticaria (20.7%). The most common class of drugs implicated was NSAIDs in 37.2% of patients followed by antimicrobials in 30.3% of patients. The males in our study outnumbered the females. Conclusion The clinical patterns and causative agents observed during our study were similar to those observed in other studies except for few variations. When a patient is exposed to new drugs, each time the pharmacokinetic and pharmacodynamic conditions are different. So outcome of drug intake is unpredictable. |
| Starting Page | 158 |
| Ending Page | 163 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| Volume Number | 27 |
| Alternate Webpage(s) | http://www.jpad.com.pk/index.php/jpad/article/download/1084/978 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
