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Facile One-Pot Synthesis of 1,3,5-Trisubstituted Pyrazoles from α,β-Enones
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kim, Ko Hoon Moon, Hye Ran Kim, Jae Nyoung |
| Copyright Year | 2014 |
| Abstract | E-mail: kimjn@chonnam.ac.krReceived January 27, 2014, Accepted February 12, 2014A practical and efficient one-pot synthesis of 1,3,5-trisubstituted pyrazoles from α,β-enones and arylhydrazinehydrochlorides has been developed. The pyrazoles were formed via a tandem formation of the correspondingpyrazolines and an acid-catalyzed aerobic oxidation process.Key Words : Pyrazoles, One-pot synthesis, Aerobic oxidation, α,β-Enones Introduction1,3,5-Trisubstituted pyrazolines are important heterocycliccompounds which can be prepared from substituted hydra-zines and α,β-enones. The oxidation of these pyrazolinesprovides the corresponding pyrazoles, which are known topossess diverse biological activities. |
| Starting Page | 1692 |
| Ending Page | 1696 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.5012/bkcs.2014.35.6.1692 |
| Volume Number | 35 |
| Alternate Webpage(s) | http://ocean.kisti.re.kr/downfile/volume/chemical/JCGMCS/2014/v35n6/JCGMCS_2014_v35n6_1692.pdf |
| Alternate Webpage(s) | https://doi.org/10.5012/bkcs.2014.35.6.1692 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |