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Prospective evaluation of the role of routine cardiac troponin T measurement to identify left ventricular ejection fraction < 40% after first myocardial infarction.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Rose, Adam J. John, Cockcroft Canepa-Anson, Rudolph Joseph, Shantha P. |
| Copyright Year | 2003 |
| Abstract | Serial measurements of creatine kinase (CK) and its MB isoenzyme (CK-MB) and calculation of area under the curve (AUC) or peak value can be used to estimate infarct size. Peak values usually occur 20–24 hours postinfarction but release kinetics are affected by reperfusion (spontaneous or therapeutic). Regular, frequent samples must be obtained following admission, not a convenient approach for busy clinical or nursing staff. In a previous retrospective study we demonstrated that an angiographically determined left ventricular ejection fraction (LVEF) < 40 % could be identified by a single cardiac troponin T (cTnT) measurement at the diagnostically efficient time point of 12–24 hours from admission. We performed a larger prospective study and compared the measurement of cTnT and peak CK with early estimation of LVEF by echocardiography. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://heart.bmj.com/content/heartjnl/89/5/559.full.pdf |
| PubMed reference number | 12695471v1 |
| Volume Number | 89 |
| Issue Number | 5 |
| Journal | Heart |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Area Under Curve Artificial cardiac pacemaker Creatine Kinase MB Isoenzyme Echocardiography Ejection fraction (procedure) Isoenzymes Large Left ventricular ejection fraction Myocardial Infarction Reperfusion Therapy Structure of Broca's area Troponin T Troponin T, Cardiac Muscle |
| Content Type | Text |
| Resource Type | Article |
