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Starburst cells nondirectionally facilitate the responses of direction-selective retinal ganglion cells.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chiao, Chuan-Chin |
| Copyright Year | 2002 |
| Abstract | The mechanism of direction selectivity in retinal ganglion cells remains controversial. An important issue is how the starburst amacrine cells, which are known to provide a major synaptic input to the direction-selective ganglion cells, participate in the directional discrimination. Here, we present evidence that the cholinergic outputs of the starburst cells affect the responses of the ganglion cells symmetrically; they provide a feedforward excitation that facilitates the response of the ganglion cells to movement in both the preferred and null directions. This seems to place a constraint on models of the directional discrimination in which the starburst cells participate, namely, that their cholinergic synapses be nondirectional in their effects on the ganglion cells. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://nthur.lib.nthu.edu.tw/dspace/retrieve/111657/2050130010010.pdf |
| Alternate Webpage(s) | http://nthur.lib.nthu.edu.tw/retrieve/111657/2050130010010.pdf |
| PubMed reference number | 12486140v1 |
| Volume Number | 22 |
| Issue Number | 24 |
| Journal | The Journal of neuroscience : the official journal of the Society for Neuroscience |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Excitation Ganglion cell Null Value Retina Retinal Ganglion Cells Synapses |
| Content Type | Text |
| Resource Type | Article |
