[Determination of seven strobilurin fungicide residues in Chinese herbs by liquid chromatography-tandem mass spectrometry coupled with solid phase extraction].

Content Provider	Semantic Scholar
Author	Zhang, Yule Huang, Chaoqun Zhu, Xiaoyu Chen, Xiaomei Mo, Weimin
Copyright Year	2013
Abstract	An LC-MS/MS method was developed for the simultaneously determination of seven strobilurin fungicide residues in Chinese herbs. The strobilurin fungicides include Z-metominostrobin, kresoxim-methyl, dimoxystrobin, picoxystrobin, pyraclostrobin, azoxystrobin and trifloxystrobin. The sample was extracted with ethyl acetate and cleaned-up by an amino SPE column. The seven strobilurin fungicide residues were separated on a C18 column with gradient elution of 1.0 per thousand formic acid and methanol as mobile phases, and detected by ESI-MS in positive ion and selective reaction monitoring (SRM) mode. External standard method was used to the quantification with good linear relationships (r > or = 0. 996). The LOQs were 2 micro g/kg for dimoxystrobin, picoxystrobin and trifloxystrobin, 4 mciro g/kg for pyraclostrobin and azoxystrobin, 10 micro g/kg for Z-metominostrobin and kresoxim-methyl. The recoveries were from 60.4% to 110% with the RSDs between 1.2% and 17%. The developed method is suitable for the determination and confirmation of the seven strobilurin fungicide residues in the three of Eight Zhes ( Ophiopogon japonicus (Thunb.), Scrophularia ningpoensis Hemsl. and Corydalis yanhusuo W T Wang).
File Format	PDF HTM / HTML
DOI	10.3724/sp.j.1123.2012.10021
PubMed reference number	23786000
Journal	Medline
Volume Number	31
Issue Number	3
Journal	Se pu = Chinese journal of chromatography
Alternate Webpage(s)	http://www.chrom-china.com/fileup/PDF/sp1210021.pdf
Alternate Webpage(s)	https://doi.org/10.3724/sp.j.1123.2012.10021
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article