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Cancers du Larynx à Brazzaville : Difficultés de Prise en Charge et Survie des Patients
| Content Provider | Semantic Scholar |
|---|---|
| Author | Dzon, Harrol Boris Otouana Diembi, S. Ngouoni, Gc Bolenga, Liboko A. Tsierie-Tsoba, A. Odzili, Fa Itiere Ondzotto, Gontran |
| Copyright Year | 2019 |
| Abstract | RESUME Objectif. Decrire la prise en charge des cancers du larynx et degager les principaux facteurs de risque influencant la survie. Materiels et methodes. L’etude a ete menee sur une periode de 10 ans (janvier 2009 a decembre 2018) dans les services d’ORL et d’oncologie medicale du Centre Hospitalier Universitaire de Brazzaville. Les patients suivis pour cancer du larynx et ayant un dossier medical complet ont ete inclus. Tous disposaient d’un bilan morphologique et biologique comprenant la pan-endoscopie des voies aero-digestives superieures, le scanner cervico-thoracique et le type histopathologique de la tumeur. Les parametres etudies etaient sociodemographiques, cliniques, anatomopathologiques et la survie des patients. Resultats. Un total de 46 patients (44 hommes et 2 femmes) avec un cancer du larynx ont ete colliges, soit 43,8% des cancers ORL et cervico-faciaux. Leur âge moyen etait de 61 ans. Le tabac et l’alcool etaient les principaux facteurs de risque. Le delai moyen de consultation etait de huit mois. La proportion au stade tardif T4 au moment du diagnostic etait de 85%. Le type histopathologique retrouve chez tous les patients etait le carcinome epidermoide bien differencie. Le siege glotto-sus-glottique representait 76% des cas. En l’absence de radiotherapie, tous les patients au stade T4 ont beneficie d’une chimiotherapie palliative alors que ceux diagnostiques aux stades T2 (2%) et T3 (13%) ont subi une laryngectomie. Le taux de survie globale etait estime a 15%. Conclusion. La frequence des cancers du larynx n’est pas negligeable a Brazzaville. La difficulte de prise en charge est liee au lent delai de consultation justifiant les stades tardifs au moment du diagnostic et aussi a l’absence de radiotherapie responsable d’une mauvaise survie des patients. ABSTRACT Objective. To describe the management of laryngeal cancers and the main risk factors influencing survival in our setting. Materials and methods. This transversal study was conducted over a period of 10 years (2009-2018) in the departments of ENT medical oncology of the University Teaching Hospital of Brazzaville. All Patients with laryngeal cancer and a complete medical record were included. Morphological and biological assessment including pan-endoscopy of the upper aero-digestive tract, cervico-thoracic CT and histopathological type of the tumor were available for all aptients. Our parameters of study were sociodemography, clinical, pathological and patient survival. Results. A total of 46 patients were enrolled (44 male, 2 female) representing 43.8% of ENT and cervicofacial cancers. Their average age was 61 years. Tobacco and alcohol were the main risk factors and the average consultation time was 8 months justifying the proportion of the late stage T4 (85%) at the time of diagnosis. Histopathology found a well-differentiated squamous cell carcinoma in all patients. Localization was a glottis and supra glottis in 76% of patients. Since radiotherapy was not available, all T4 patients received palliative chemotherapy, while those diagnosed at T2 (2%) and T3 (13%) had laryngectomy. The overall survival rate was estimated at 15%. Conclusion. Laryngeal cancers is present in Brazzaville. The difficulty of management is related to the slow consultation period justifying the late stages at the time of diagnosis and also to the absence of radiotherapy responsible for poor patient survival. |
| File Format | PDF HTM / HTML |
| Volume Number | 21 |
| Alternate Webpage(s) | https://www.hsd-fmsb.org/index.php/hsd/article/download/1762/pdf_855 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
