NDLI: Central corneal thickness determined with optical coherence tomography in various types of glaucoma.

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Central corneal thickness determined with optical coherence tomography in various types of glaucoma.

Content Provider	Semantic Scholar
Author	Bechmann, Martin Thiel, Martin J. Roesen, B. Ulbig, Michael Werner Ludwig, Klaus
Copyright Year	2000
Abstract	AIMS To evaluate central corneal thickness determined by optical coherence tomography (OCT) in various types of glaucoma, and its influence on intraocular pressure (IOP) measurement. METHODS Central corneal thickness (CCT) was determined by using OCT in 167 subjects (167 eyes). 20 had primary open angle glaucoma (POAG), 42 had low tension glaucoma (LTG), 22 had ocular hypertension (OHT), 10 had primary angle closure glaucoma (AC), 24 had pseudoexfoliation glaucoma (PEX), 13 had pigmentary glaucoma (PIG), and 36 were normal. RESULTS CCT was significantly higher in ocular hypertensive subjects (593 (SD 35) microm, p <0.0001) than in the controls (530 (32) microm), whereas patients with LTG (482 (28) microm, p < 0. 0001), PEX (493 (33) microm, p <0.0001), and POAG (512 (30) microm, p <0.05) showed significantly lower readings. There was no statistically significant difference between the controls and patients with PIG (510 (39) microm) and AC (539 (37) microm). CONCLUSIONS Because of thinner CCT in patients with LTG, PEX, and POAG this may result in underestimation of IOP, whereas thicker corneas may lead to an overestimation of IOP in subjects with OH. By determining CCT with OCT, a new and precise technique to measure CCT, this study emphasises the need for a combined measurement of IOP and CCT in order to obtain exact IOP readings.
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://bjo.bmj.com/content/bjophthalmol/84/11/1233.full.pdf
PubMed reference number	11049946v1
Volume Number	84
Issue Number	11
Journal	The British journal of ophthalmology
Language	English
Access Restriction	Open
Subject Keyword	Angle Closure Glaucoma Central corneal thickness Cornea Exfoliation Syndrome Eye Glaucoma, Primary Open Angle Hypertensive disease Low Tension Glaucoma Ocular Hypertension Patients Physiologic Intraocular Pressure Primary angle-closure glaucoma Pseudoexfoliation Reading (activity) Tomography, Optical Coherence tomography
Content Type	Text
Resource Type	Article

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