NDLI: Calcium transport and fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene in sarcoplasmic reticulum from normal and ethanol-tolerant rats

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Calcium transport and fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene in sarcoplasmic reticulum from normal and ethanol-tolerant rats

Content Provider	Semantic Scholar
Author	Mrak, Robert E.
Copyright Year	1983
Abstract	Sarcoplasmic reticulum (SR) of high purity and functional integrity was isolated from skeletal muscle of normal and ethanol-tolerant rats. Ethanol at low concentrations (0.1 to 0.2 M), added in vitro to isolated SR, resulted in slight inhibition of both calcium loading and calcium-stimulated ATPase rates. Higher concentrations of ethanol resulted in further inhibition of calcium loading, but not of calcium-stimulated ATPase. Fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH) in isolated SR membranes showed a small decrease in anisotropy with the addition of ethanol in vitro. Sarcoplasmic reticulum from normal and ethanol-tolerant rats did not differ in calcium pump function or in fluorescence polarization of DPH, in the presence or absence of ethanol.
Starting Page	573
Ending Page	581
Page Count	9
File Format	PDF HTM / HTML
DOI	10.1016/0014-4886(83)90308-4
PubMed reference number	6221940
Journal	Medline
Volume Number	80
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/0014488683903084
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/0014488683903084?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://doi.org/10.1016/0014-4886%2883%2990308-4
Journal	Experimental Neurology
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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