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Transvaginal ultrasound studies of vascular and morphological changes in uteri exposed to diethylstilbestrol in utero.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sergeant, Paul T. Awada, Azzam Bied-Damon, V. Gaucherand, Pascal Boisson, Catherine Guibaud, Stéphane Benchaib, M. Rudigoz, R. C. |
| Copyright Year | 1996 |
| Abstract | The aim of this prospective study was to establish complementary data of uteri exposed to diethylstilbestrol (DES) in utero for transvaginal analysis and vascularity changes during the menstrual cycle. A total of 28 women with DES-exposed uteri were compared with 60 non-exposed women. Transvaginal ultrasound and colour Doppler imaging were performed on days 5 and 22 of the menstrual cycle. Uteri were measured on sagittal and transverse scans. Uterine length, width, thickness and uterine cavity length and width were measured. Uterine volume and uterine cavity area were calculated. DES-exposed uterine volume was equal to 31.84 +/- 3.37 cm3. The cavity area of DES-exposed uterus was equal to 35.85 +/- 3.93 cm2. Cervix length of DES-exposed uterus was significantly smaller than that of non-exposed uterus. The uterine artery pulsatility index (PI) of DES-exposed uterus was significantly higher than that of normal uterus. Blood flow remained stable throughout the menstrual cycle. The PI of DES-exposed uterus remained stable during the menstrual cycle, as in non-exposed uterus, and it decreased during the luteal phase. This lack of modification in vascularity of DES-exposed uterus may explain miscarriages and obstetric complications such as intrauterine growth retardation or pre-eclampsia. The data may have implications for the assessment of reproductive status and the design of future studies on disorders of implantation in DES-exposed uterus. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.sbri.fr/files/publications/salle%2096%20hum%20reprod11.pdf |
| PubMed reference number | 8981149v1 |
| Volume Number | 11 |
| Issue Number | 11 |
| Journal | Human reproduction |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Body cavities Citric Acid Cycle Dental caries Diethylstilbestrol Eclampsia Fetal Growth Retardation Intrauterine Luteal Phase Menstrual cycle Menstruation Pre-Eclampsia Sagittal plane Small Spontaneous abortion Structure of uterine artery Ultrasonography Uterine Corpus Carcinosarcoma Uterine cavity Uterus milliliter transvaginal ultrasound width |
| Content Type | Text |
| Resource Type | Article |