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One‐Pot, Three‐Step Preparation of Alkyl and Aryl Alkylcarbamates from S‐Methyl N‐Alkylthiocarbamates.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Artuso, Emma Degani, Iacopo Fochi, Rita Magistris, Claudio |
| Copyright Year | 2008 |
| Abstract | SYNTHESIS 2008, No. 10, pp 1612–1618xx.xx.2008 Advanced online publication: 27.03.2008 DOI: 10.1055/s-2008-1072573; Art ID: Z03508SS © Georg Thieme Verlag Stuttgart · New York Abstract: A general procedure for the synthesis of alkyl and aryl alkylcarbamates starting from the corresponding S-methyl N-alkylthiocarbamates is described. This procedure consists of three steps that are carried out in a one-pot fashion, without isolating the intermediate N-alkylcarbamoyl chlorides or alkyl isocyanates. All the target products were obtained in high yields (16 examples, average yield 91%). To be noted is the recovery of a co-product of industrial interest, dimethyl disulfide, in a half mole amount for each mole of thiocarbamate, with complete exploitation of the reagent. The alkyl isocyanates, if required, can also be isolated in high yields. |
| Starting Page | 1612 |
| Ending Page | 1618 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/chin.200838056 |
| Volume Number | 39 |
| Alternate Webpage(s) | http://www.xiuzhengrd.com/ejournals/pdf/synthesis/doi/10.1055/s-2008-1072573.pdf |
| Alternate Webpage(s) | https://doi.org/10.1002/chin.200838056 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |