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Three-Dimensional Regional Left Ventricular Deformation from Digital Sonomicrometry
| Content Provider | Semantic Scholar |
|---|---|
| Author | Dione, Donald P. Shi, Pengcheng Smith, Wayne Deman, P. Soares, Jason W. Duncan, James S. Sinusas, Albert J. |
| Copyright Year | 1997 |
| Abstract | Understanding how the left ventricle deforms in 3D and how this deformation is altered with coronary occlusion may lead to the development of non-invasive imaging techniques to determine the extent of permanent injury. To determine regional 3D strains in the left ventricle of the heart we employed digital sonomicrometry, with high temporal and spatial resolution. Two cubic arrays of 8 omnidirectional transceiver crystals were implanted in two regions of the left ventricle in an open chest canine preparation (n = 6). Additional crystals were used to define a fixed external reference space and the long axis of the ventricle. Using ultrasound transit time the distances between all the crystals were recorded. A multidimensional scaling technique was then applied to transform the distances to 3D crystal coordinates. A least squares fit of the displacement field was applied to calculate homogeneous strains for each cube. Cardiac specific directions were determined and strains rotated into the local coordinate space. This technique was applied preand postcoronary occlusion. Alterations in strain patterns were evident in the ischemic region and subtle temporal changes in the control region. Thus, digital sonomicrometry, with high temporal and spatial resolution, enhances our ability to analyze regional left ventricular 3D strain patterns. Keywords— Coronary occlusion, Myocardial deformation, Strain measurement, Sonomicrometry |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://ipag.med.yale.edu/papers/embs.pdf |
| Alternate Webpage(s) | http://noodle.med.yale.edu/papers/embs.pdf |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | 3D film Apache Axis Axis vertebra Computer simulation Coronary Occlusion Crystal oscillator Cube Dosage Form Cubic function Displacement mapping Distance Heart Ventricle Image scaling Implants Least squares Left ventricular structure Logical volume management Multidimensional scaling Myocardial Ischemia Occlusion of artery (disorder) Processor Control Region Psychologic Displacement Remote control Repetitive strain Retinal Vein Occlusion Stratification Test scaling Transceiver Device Component Ventricular Remodeling |
| Content Type | Text |
| Resource Type | Article |
