Loading...
Please wait, while we are loading the content...
Similar Documents
Propolis supplementation improves glycemic and antioxidant status in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled study.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Afsharpour, Fatemeh Javadi, Maryam Seyed Hashemipour, Sima Koushan, Yaghob Haghighian, Hossein Khadem |
| Copyright Year | 2019 |
| Abstract | OBJECTIVES The prevalence of type 2 diabetes has risen dramatically in recent years. There are many different safe therapies used for diabetes and also number of natural supplements that can be used to manage diabetes. We assessed the effect of oral propolis supplementation on blood glucose, insulin resistance and antioxidant status in type 2 diabetes. METHODS We conducted a randomized, double-blinded, placebo-controlled trial for 8-week. Sixty two patients with type 2 diabetes (30-55 years of age) were randomly assigned in two group, propolis (n = 31) and placebo (n = 31). Patients were given doses of 500 mg, three times a day (1500 mg), of propolis or placebo three time a day. The fasting blood sugar (FBS), two-hour postprandial glucose (2-hp), insulin, insulin resistance (IR), hemoglobin A1c (HbA1c), total antioxidant capacity (TAC) and activity of glutathione peroxidase (GPx) and superoxide dismutase (SOD) were measured at the beginning and end of the study. Statistical analysis was performed using SPSS software. RESULTS After two month, FBS, 2-hp, insulin, IR, HbA1c was significantly decreased in patients treated with propolis compared with placebo group (p < 0.05). Additionally intake of propolis significantly increased the blood levels of TAC and activity of GPx and SOD (p < 0.05). CONCLUSION Propolis treatment can be helpful as a diet supplement in patients with type 2 diabetes through improvement in glycemic status, reduction in insulin resistance and amelioration in antioxidant status. This supplement without side effects can increase the effectiveness of prescribing drugs in diabetes. |
| Starting Page | 283 |
| Ending Page | 288 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.ctim.2019.03.001 |
| PubMed reference number | 30935545 |
| Journal | Medline |
| Volume Number | 43 |
| Alternate Webpage(s) | http://eprints.qums.ac.ir/8951/1/Propolis%20supplementation.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/j.ctim.2019.03.001 |
| Journal | Complementary therapies in medicine |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
