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Neonatal thrombocytopenia and platelet transfusion - a UK perspective.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Carr, Robert Scott Kelly, Anne M. Williamson, Lorna McLeod |
| Copyright Year | 2015 |
| Abstract | Five percent of newborn infants admitted to UK neonatal units during a recent study developed a platelet count <60 × 10(9)/l, and 60% of these were transfused platelets. This review summarises the common causes and mechanisms of thrombocytopenia in the newborn. Relevant evidence relating the platelet count to the risk of haemorrhage is reviewed, and current UK guidance on transfusion thresholds outlined. The UK policy for the provision of platelets for transfusion to neonates is described, including the particular requirements for neonatal allo-immune thrombocytopenia. Finally, we look towards the future and prospects for reducing the need to expose newborns to donor-derived platelets. |
| Starting Page | 1 |
| Ending Page | 7 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.karger.com/Article/Pdf/365163 |
| PubMed reference number | 25301082v1 |
| Alternate Webpage(s) | https://doi.org/10.1159/000365163 |
| DOI | 10.1159/000365163 |
| Journal | Neonatology |
| Volume Number | 107 |
| Issue Number | 1 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Allopurinol Blood Platelet Disorders Blood Platelets Hemorrhage Infant, Newborn Neonatal Alloimmune Thrombocytopenia Platelet Count measurement |
| Content Type | Text |
| Resource Type | Article |
