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A Fully Automated Continuous‐Flow Platform for Fluorescence Quenching Studies and Stern–Volmer Analysis
| Content Provider | Semantic Scholar |
|---|---|
| Author | Kuijpers, Koen P. L. Bottecchia, Cecilia Cambié, Dario Drummen, Koen König, Niels J. Noël, Timothy |
| Copyright Year | 2018 |
| Abstract | Herein, we report the first fully automated continuous-flow platform for fluorescence quenching studies and Stern-Volmer analysis. All the components of the platform were automated and controlled by a self-written Python script. A user-friendly software allows even inexperienced operators to perform automated screening of novel quenchers or Stern-Volmer analysis, thus accelerating and facilitating both reaction discovery and mechanistic studies. The operational simplicity of our system affords a time and labor reduction over batch methods while increasing the accuracy and reproducibility of the data produced. Finally, the applicability of our platform is elucidated through relevant case studies. |
| Starting Page | 11278 |
| Ending Page | 11282 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/anie.201805632 |
| PubMed reference number | 29992682 |
| Journal | Medline |
| Volume Number | 57 |
| Alternate Webpage(s) | https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/60/3f/ANIE-57-11278.PMC6120497.pdf |
| Alternate Webpage(s) | https://doi.org/10.1002/anie.201805632 |
| Journal | Angewandte Chemie |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |