NDLI: Hypercapnie induite par l’oxygénothérapie : mythe ou réalité ?

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Hypercapnie induite par l’oxygénothérapie : mythe ou réalité ?

Content Provider	Semantic Scholar
Author	Barbaz, Mathilde Guillon, Antoine
Copyright Year	2012
Abstract	RésuméL’oxygénothérapie est réputée responsable d’hypercapnie délétère chez l’insuffisant respiratoire chronique. Si les mécanismes en sont explorés depuis plus de 60 ans, aucun d’entre eux n’est incriminé de façon univoque. Le mécanisme prépondérant paraît être une modification des rapports ventilation/perfusion, mais son degré d’implication dans le phénomène varie, probablement en fonction de la sévérité de la maladie sous-jacente. Les études cliniques sont plus récentes, mais sont contradictoires. Il semble toutefois que, chez l’insuffisant respiratoire chronique, la rétention de CO2 en réponse à l’oxygénothérapie soit inconstante, et ses effets délétères mal évalués. Cependant, la titration de l’oxygène chez ces patients est dépourvue d’effet délétère connu, et semble une option raisonnable.AbstractOxygen therapy is assumed to increase hypercapnia in chronic obstructive pulmonary disease (COPD). If the mechanisms have been investigated since over 60 years, none of them is formally involved. The predominant mechanism appears to be a change in the ventilation/perfusion ratio, but the degree of its involvement varies, probably depending on the severity of the underlying disease. Clinical studies are more recent, however with contradictory results. It seems that only a small part of COPD patients experienced CO2 retention during oxygen therapy; side-effects are unclear. Nevertheless, titrated administration of oxygen to patients with COPD appears a safe procedure without deleterious effects, provided that a sufficient PaO2 can be obtained.
Starting Page	73
Ending Page	79
Page Count	7
File Format	PDF HTM / HTML
DOI	10.1007/s13546-011-0439-4
Volume Number	21
Alternate Webpage(s)	http://www.srlf.org/wp-content/uploads/2015/11/1201-Reanimation-vol21-N1-p73_p79.pdf
Alternate Webpage(s)	https://page-one.springer.com/pdf/preview/10.1007/s13546-011-0439-4
Alternate Webpage(s)	https://doi.org/10.1007/s13546-011-0439-4
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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